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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLIS3
All Species:
11.21
Human Site:
S580
Identified Species:
30.83
UniProt:
Q8NEA6
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEA6
NP_001035878.1
775
83667
S580
V
P
P
P
H
P
V
S
H
P
S
P
G
H
N
Chimpanzee
Pan troglodytes
Q5IS56
1580
169881
S714
P
G
G
Q
S
S
C
S
S
Q
Q
S
P
I
S
Rhesus Macaque
Macaca mulatta
XP_001083553
907
97858
S712
V
P
P
P
H
P
V
S
H
P
S
P
G
H
N
Dog
Lupus familis
XP_541295
826
88622
G630
V
P
P
P
H
T
V
G
H
P
S
P
G
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6XP49
780
83863
S585
G
P
P
P
H
P
V
S
H
P
S
P
G
H
N
Rat
Rattus norvegicus
Q5XIU2
638
68981
E444
R
T
A
H
N
D
T
E
P
I
E
E
E
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P55879
663
73088
S469
S
S
C
S
S
E
P
S
P
L
G
S
T
N
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074076
787
86851
T589
S
P
T
D
D
L
Y
T
V
F
T
L
N
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19538
1397
153262
L685
V
R
A
S
D
S
L
L
T
Y
S
P
D
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.3
79.5
83
N.A.
85.3
21.5
N.A.
N.A.
26
N.A.
37.6
N.A.
23.5
N.A.
N.A.
N.A.
Protein Similarity:
100
30.8
82.3
87
N.A.
89.6
35.8
N.A.
N.A.
41.4
N.A.
50.3
N.A.
34
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
80
N.A.
93.3
0
N.A.
N.A.
13.3
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
80
N.A.
93.3
6.6
N.A.
N.A.
20
N.A.
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
23
12
0
0
0
0
0
0
12
12
0
% D
% Glu:
0
0
0
0
0
12
0
12
0
0
12
12
12
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
12
12
12
0
0
0
0
12
0
0
12
0
45
0
0
% G
% His:
0
0
0
12
45
0
0
0
45
0
0
0
0
34
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
12
12
12
0
12
0
12
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
0
12
12
56
% N
% Pro:
12
56
45
45
0
34
12
0
23
45
0
56
12
0
12
% P
% Gln:
0
0
0
12
0
0
0
0
0
12
12
0
0
34
0
% Q
% Arg:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
23
12
0
23
23
23
0
56
12
0
56
23
0
0
12
% S
% Thr:
0
12
12
0
0
12
12
12
12
0
12
0
12
0
0
% T
% Val:
45
0
0
0
0
0
45
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _